Trichloroacetonitrile as a Source of Positive Chlorine Ion for Trapping Huisgen's Zwitterions |
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| Authors: | Issa Yavari Samira Nasiri‐Gheidari |
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| Affiliation: | 1. Department of Chemistry, Tarbiat Modares University, P.O. Box, 14115‐175 Tehran, Iran, (phone: +98‐21‐82883465;2. fax: +98‐21‐82883455) |
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| Abstract: | The zwitterionic 1 : 1 intermediates generated by addition of N‐heterocycles to activated acetylenes are trapped by trichloroacetonitrile to afford 1,2‐ or 1,4‐disubstituted N‐heterocycles in moderate to good yields under mild reaction conditions. |
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| Keywords: | Acetonitrile, trichloro‐ Activated acetylene Multicomponent reactions Pyridines, 1,4‐dihydro‐ Isoquinolines, 1,2‐dihydro‐ Huisgen's zwitterions |
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