Convenient Synthesis of 3,5‐Biscarbamoyl‐pyridine Derivatives |
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| Authors: | Xiayun Wang Yiwen Zhu Min Zhang Dongliang Lu Qun Qian Yali Chen Weiguo Cao Liping Song Hongmei Deng |
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| Affiliation: | 1. Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China;2. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China;3. Instrumental Analysis and Research Center, Shanghai University, Shanghai 200444, China |
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| Abstract: | An efficient and convenient method for synthesis of 3,5‐bis‐carbamoyl‐2,6‐dimethylpyridine derivatives was achieved in good to excellent yields by reaction of anilines with 3,5‐bis(3′,5′‐dimethyl‐1′‐pyrazolyl‐carbonyl)‐2,6‐dimethylpyridine, in which pyrazoles served as leaving groups. The structures of products were confirmed by spectra data and microanalysis. |
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| Keywords: | heterocycles amide aromatic amine synthesis |
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