Cycloartane Glycosides from Three Species of Astragalus (Fabaceae) |
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| Authors: | Jens Linnek Anne‐Claire Mitaine‐Offer Tomofumi Miyamoto Chiaki Tanaka Thomas Paululat Sibel Avunduk Özgen Alankuş‐Çalişkan Marie‐Aleth Lacaille‐Dubois |
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| Affiliation: | 1. Laboratoire de Pharmacognosie, Unité de Molécules d'Intérêt Biologique (UMIB EA 3660), Faculté de Pharmacie, Université de Bourgogne, 7 Bd. Jeanne D'Arc, BP 87900, F‐21079 Dijon Cedex, (phone: +33‐3‐80393229;2. fax: +33‐3‐80393300);3. Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan;4. Department of Organic Chemistry II, University of Siegen, Adolf‐Reichwein‐Strasse 2, D‐57068 Siegen;5. Medical Laboratory Programme, Vocational School of Health Care, Mugla University, Mugla, 48187 Turkey;6. Department of Chemistry, Faculty of Sciences, Ege University 2, Bornova, Izmir, 35100 Turkey |
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| Abstract: | Nine cycloartane‐type glycosides were isolated from three species of the genus Astragalus (Fabaceae): From the aerial parts of A. cicer L., two new saponins, cicerosides A and B ( 1 and 2 , resp.), i.e., a tetradesmosidic and tridesmosidic cycloartane‐type glycosides besides one known compound, from the roots of A. sempervirens Lam ., one known saponin, and from the roots of A. ptilodes Boiss . var. cariensis Boiss ., five known compounds. Their structures were established mainly by 600‐MHz 2D‐NMR techniques (1H,1H‐COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectroscopy. |
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| Keywords: | Astragalus species Saponins Cicerosides A and B Cycloartane‐type glycosides Glycosides |
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