Synthesis and reactions of 18β-glycyrrhetaldehyde |
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Authors: | S. Rozen I. Shahak E.D. Bergmann |
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Affiliation: | Department of Organic Chemistry, The Hebrew University of Jerusalem, Israel |
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Abstract: | 18β-Glycyrrhetaldehyde has been prepared by two methods and its synthetic potential has been studied. In spite of some steric hindrance, it reacts on the whole quite normally. The aldehyde has been used for the preparation of derivatives with side-chains at C-20 which resemble those in the corticoid hormones. |
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