An Efficient and Practical Synthesis of Dibenzo[d,f][1,3]‐dioxepines from 2,2′‐Dihydroxybiphenyl with Terminal Alkynes Catalyzed by Lewis Acid TiCl4 |
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| Authors: | Haisheng Wu Jin Yang Prof Dr Lei Wang |
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| Institution: | 1. Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, China;2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China |
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| Abstract: | A synthetic strategy toward the cyclic addition of 2,2′‐dihydroxybiphenyl to terminal alkynes has been developed using Lewis acid TiCl4 as catalyst. The reactions generated dibenzod,f]1,3]dioxepines derivatives in good yields with excellent regio‐selectivity in the presence of catalytic amount of TiCl4 under mild reaction conditions. |
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| Keywords: | cyclic addition 2 2′ ‐dihydroxybiphenyl terminal alkynes region‐selectivity Lewis acid TiCl4 |
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