Synthesis and biological screening of 4‐(3,3‐dimethylspiro{bicyclo[2.2.1]heptan‐2,5′‐isoxazoline‐2}‐ 3′‐yl)‐2‐aryl‐2,3‐dihydro‐1H‐1,5‐benzodiazepines |
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| Authors: | Tahira Naqvi Deepali Mahajan Rattan Lal Sharma Inshad Ali Khan Kamal K. Kapoor |
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| Affiliation: | 1. Department of Chemistry, University of Jammu, Jammu 180006, India;2. Department of Biotechnology, Indian Institute of Integrative Medicine (CSIR), Jammu 180001, India |
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| Abstract: | A series of novel 4‐(3,3‐dimethylspiro{bicyclo[2.2.1]heptan‐2,5′‐isoxazoline‐2}‐3′‐yl)‐2‐phenyl‐2,3‐dihydro‐1H‐1,5‐benzodiazepines were synthesized. These molecules were screened in vitro for their antifungal and antibacterial activity, and none of the tested compounds showed promising antimicrobial or antifungal activity. J. Heterocyclic Chem., 2011. |
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