Two New Cyclic Pentapeptides from the Marine‐Derived Fungus Aspergillus versicolor |
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| Authors: | Sheng‐Xin Cai Tian‐Jiao Zhu Qian‐Qun Gu De‐Hai Li |
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| Affiliation: | 1. Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P.?R. China, (phone: +86‐532‐82031619;2. fax: +86‐532‐82033054) |
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| Abstract: | Two new cyclic pentapeptides, named versicotides A ( 1 ) and B ( 2 ), were obtained from a marine‐derived fungus strain ZLN‐60, identified as Aspergillus versicolor. Their structures were established on the basis of chemical and spectroscopic evidence. Versicotides are new cyclic pentapeptides which contain an L ‐alanine residue, two anthranilic acid (=2‐aminobenzoic acid) residues, and two N‐methyl‐L ‐alanine residues. Antitumor activities were evaluated by the SRB and MTT methods. |
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| Keywords: | Aspergillus versicolor Fungi Peptides Versicotides A and B Cytotoxic activity |
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