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Two New Abietane Diterpenoids from the Stems of Clerodendrum kaichianum P. S. Hsu
Authors:Mingfeng Xu  Lianqing Shen  Kuiwu Wang  Qizhen Du
Affiliation:1. College of Food Science and Biotechnology Engineering, Zhejiang Gongshang University, Hangzhou 310035, P.?R. China, (phone: +86‐571‐88071024‐7575;2. fax: +86‐571‐88071024‐7575)
Abstract:Two new abietane diterpenoids, named 17‐hydroxyteuvincenone G ( 1 ) and 17‐hydroxyteuvincen‐5(6)‐enone G ( 2 ), together with four known diterpenoids, were isolated from the stems of Clerodendrum kaichianum P. S. Hsu . Their structures were elucidated by extensive NMR and MS analyses, and by comparison with literature data. The new compounds showed significant cytotoxicities against the HL‐60 and A‐549 tumor cell lines.
Keywords:Clerodendrum kaichianum  Abietane diterpenoids  Diterpenoids  Cytotoxic activity
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