Capillary electrophoresis determination of nonsteroidal anti‐inflammatory drugs in wastewater using hollow fiber liquid‐phase microextraction |
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Authors: | Mercedes Villar Navarro María Ramos Payán Rut Fernández‐Torres Miguel A. Bello‐López Manuel Callejón Mochón Alfonso Guiráum Pérez |
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Affiliation: | Department of Analytical Chemistry, Faculty of Chemistry, University of Seville, Seville, Spain |
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Abstract: | The presence of pharmaceuticals in the environment due to growing worldwide consumption has become an important problem that requires analytical solutions. This paper describes a CE determination for several nonsteroidal anti‐inflammatory drugs (ibuprofen, naproxen, ketoprofen, diclofenac, ketorolac, aceclofenac and salicylic acid) in environmental waters using hollow fiber membrane liquid‐phase microextraction. The extraction was carried out using a polypropylene membrane supporting dihexyl ether and the electrophoretic separation was performed in acetate buffer (30 mM, pH 4) using ACN as the organic modifier. Detection limits between 0.25 and 0.86 ng/mL were obtained, respectively. The method could be applied to the direct determination of the seven anti‐inflammatories in wastewaters, and five of them have been determined or detected in different urban wastewaters. |
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Keywords: | CE Hollow fiber liquid‐phase microextraction Nonsteroidal anti‐inflammatory drugs Wastewater |
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