Indium(III) Chloride‐Catalyzed Conversion of {[(Benzyloxy)carbonyl]amino}‐Substituted Sulfones with 2‐[(Trimethylsilyl)oxy]furan: A Facile Access to γ‐Butenolactone Derivatives Containing a Protected Amino Group |
| |
| Authors: | Biswanath Das Chithaluri Sudhakar Parigi Raghavendar Reddy Jajula Kashanna |
| |
| Institution: | 1. Organic Chemistry Division‐I, Indian Institute of Chemical Technology, Hyderabad‐500?007, India, (phone: +91‐40‐7193434;2. fax: +91‐40‐7160512) |
| |
| Abstract: | Treatment of {(benzyloxy)carbonyl]amino}‐substituted sulfones 1 with 2‐(trimethylsilyl)oxy]furan ( 2 ) in the presence of InCl3 as a catalyst at room temperature produced the γ‐butenolactone derivatives 3 and 4 containing a protected amino group (Scheme 1). The products were formed in high yields (81–92%) within 3–10 h favoring the anti‐isomer 3 . |
| |
| Keywords: | Indium chloride Sulfones Furan 2‐[(trimethylsilyl)oxy]‐ γ ‐Butenolactone derivatives Catalysis |
|
