The Reaction of (N‐Isocyanimino)triphenylphosphorane with Biacetyl in the Presence of Aromatic Carboxylic Acids: Efficient One‐Pot Three‐Component Reaction for the Synthesis of 3‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐yl)‐3‐hydroxybutan‐2‐one Derivatives |
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| Authors: | Ali Ramazani Morteza Rouhani Aram Rezaei Nahid Shajari Ali Souldozi |
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| Affiliation: | 1. Chemistry Department, Zanjan University, P.O. Box 45195‐313, Zanjan, Iran, (fax: +98?241?5283100);2. Chemistry Department, Islamic Azad University – Urmia Branch, P.O. Box 969, Urmia, Iran |
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| Abstract: | Reactions of biacetyl (=butane‐2,3‐dione) with (N‐isocyanimino)triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford 3‐(5‐aryl‐1,3,4‐oxadiazol‐2‐yl)‐3‐hydroxybutan‐2‐one derivatives in high yields. |
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| Keywords: | Biacetyl Phosphorane, (N‐isocyanimino)triphenyl‐ Carboxylic acids 1,3,4‐Oxadiazoles Aza‐Wittig reaction Multicomponent reactions Passerini reaction |
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