[BMIM]Cl Catalyzed One‐Pot Synthesis of α‐Aminophosphonate Derivatives Containing a 4‐Phenoxyquinazoline Moiety under Microwave Irradiation |
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Authors: | Song Bai Baoan Song Pinaki S. Bhadury Song Yang Deyu Hu Wei Xue |
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Affiliation: | Research and Development Center for Fine Chemicals, Education Ministry Key Laboratory of Green Pesticide and Bioengineering, Guizhou University, Guiyang, Guizhou 550025, China |
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Abstract: | [BMIM]Cl catalyzed three component Mannich‐type reaction of 4‐(quinazolin‐4‐yloxy)benzenamine and aldehyde with dialkyl phosphite under microwave irradiation has been described. The salient features of the reaction leading to new α‐aminophosphonates include shorter reaction time and good yields. The method is environmentally friendly and does not require toxic catalysts or solvents. To the best of our knowledge, this is the first report for [BMIM]Cl induced one‐pot synthesis of α‐aminophosphonate derivatives. |
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Keywords: | quinazoline α ‐aminophosphonates [BMIM]Cl microwave chemistry multicomponent reaction |
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