New Isoflavone C‐Glycosides from Pueraria lobata |
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| Authors: | Guo‐Hui Li Qing‐Wen Zhang Lei Wang Xiao‐Qi Zhang Wei‐Cai Ye Yi‐Tao Wang |
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| Institution: | 1. Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau, (phone: +853?8397?4879;2. fax: +853?2884?1358);3. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, P.?R. China;4. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, P.?R. China |
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| Abstract: | Three new isoflavone C‐glycosides, along with two known isoflavone O‐glycosides, were isolated from the roots of Pueraria lobata (Willd .) Ohwi . The structures of the new compounds were elucidated as 4′,7‐dihydroxy‐3′‐methoxyisoflavone 8‐C‐β‐d‐ glucopyranosyl‐(1→6)]‐β‐d‐ glucopyranoside ( 1 ), 4′,7‐dihydroxy‐3′‐methoxyisoflavone 8‐C‐β‐d‐ apiofuranosyl‐(1→6)]‐β‐d‐ glucopyranoside ( 2 ), and 8‐C‐β‐d‐ glucopyranosyl‐4′,7‐dihydroxy‐3′‐methoxyisoflavone 4′‐O‐β‐d‐ glucopyranoside ( 3 ) on the basis of spectroscopic methods, especially 2D‐NMR and MS analyses. The known compounds isolated were identified by comparison of their physical and spectroscopic data with those reported in the literature. |
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| Keywords: | Pueraria lobata Isoflavones Glycosides |
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