Zur lokalisierung funktioneller gruppen in steroiden mit hilfe der massenspektrometrie—VII : 3,11-Dihydroxypregnan-20-one |
| |
Authors: | M Ende G Spiteller |
| |
Institution: | Organisch-Chemisches Institut der Universität Göttingen UK |
| |
Abstract: | The mass spectrometric degradation reactions of 3,11-dihydroxypregnan-20-ones concern mainly cleavage reactions in the D ring. Characteristic fragments are the ions of mass 43 combined with ions of mass 84 and 85. Equally, after single and double loss of water CH3CO? is eliminated, as well as C 15–17, C20 and C21.All spectra of 3,11-dihydroxypregnan-20-ones are characterised by a key fragment of mass 190 produced by cleavage of bonds in the B ring.Ions with an 11α-OH group show important ions of mass 124 which are dominating if the A/B ring system is cis connected. In contrast the configuration of an OH group in position 3 can hardly be deduced by the spectra. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|