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Activated Anilide in Heterocyclic Synthesis: Synthesis of New Dihydropyridines,Dihydropyridazines and Thiourea Derivatives
Authors:Ibrahim S A Hafiz  Mahmoud M M Ramiz  Ahmed A M Sarhan
Institution:1. Department of Chemistry, Faculty of Education, Suez Canal University, Arish, Egypt;2. Faculty of Electronic Engineering, Menofia University, Menouf, Egypt
Abstract:A series of new dihydropyridines, butanamide, dihydropyridazines and thiourea derivatives have been prepared through the reactions of 3‐aminopyridine ( 1 ) and N‐(pyridin‐3‐yl)‐3‐(pyridin‐3‐ylimino)butanamide 3 with some electrophilic reagents, aryl diazonium salts and isothiocyanates. Elementary analysis, MS, IR, and 1H NMR spectra confirmed the identity of the products.
Keywords:lactones  oxygen heterocycles  cis‐Wittig olefination  mono and di‐O‐benzyl ethers  cryptofolione stereoisomers
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