Glucose Biosensor Using Glucose Oxidase and Electrospun Mn2O3‐Ag Nanofibers |
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| Authors: | Shan Huang Yu Ding Yixin Liu Liang Su Raymond Filosa Jr. Yu Lei |
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| Affiliation: | 1. Biomedical Engineering Program, University of Connecticut, 191 Auditorium Road, Unit 3222, Storrs, CT 06269‐3222, USA;2. Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut, 191 Auditorium Road, Unit 3222, Storrs, CT 06269‐3222, USA fax: 860‐486‐2959 |
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| Abstract: | The highly porous Mn2O3‐Ag nanofibers were fabricated by a facile two‐step procedure (electrospinning and calcination). The structure and composition of the Mn2O3‐Ag nanofibers were characterized by SEM, TEM, XRD, EDX and SAED. The as‐prepared Mn2O3‐Ag nanofibers were then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. The biosensor shows fast response to glucose, high sensitivity (40.60 µA mM?1 cm?2), low detection limit (1.73 µM at S/N=3), low Km,app value and excellent selectivity. These results indicate that the novel Mn2O3‐Ag nanfibers‐GOD composite has great potential application in oxygen‐reduction based glucose biosensing. |
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| Keywords: | Glucose Nanofibers Electrochemistry Electrospinning Glucose oxidase |
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