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Copper‐catalyzed N‐Arylation of Imidazoles with Aryl or Heteroaryl Halides Facilitated by Dimethylglyoxime in Water
Authors:Xiangmei Wu  Weiya Hu
Affiliation:Department of Chemistry, College of Science, Lishui University, Lishui, Zhejiang 323000, China
Abstract:A combination of CuSO4/dimethylglyoxime was found to be an efficient and inexpensive catalyst system for N‐arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.
Keywords:copper  N‐arylation  nitrogen heterocycles  dimethylglyoxime  water
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