Highly Stereoselective Synthesis of 1,2‐Diorganothio‐1‐alkenes via Hydrothiolation of Alkynyl Sulfides Catalyzed by Cesium Hydroxide |
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| Authors: | Ping Tan Xianhong Yin Aihe Yu Renhua Qiu Lifen Peng Xinhua Xu Yalei Zhao Ruiren Tang |
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| Institution: | 1. Department of Biological and Chemical Engineering, Hunan Mechanical and Electrical Polytechnic, Changsha, Hunan 410151, China;2. College of Chemistry and Ecological Engineering, Guangxi University for Nationalities, Nanning, Guangxi 530006, China;3. College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China;4. College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, China |
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| Abstract: | In the presence of catalytic amount of cesium hydroxide, the hydrothiolation of alkynyl sulfides occurred at room temperature in DMF under nitrogen atmosphere to afford exclusive (Z)‐1,2‐diorganothio‐1‐alkene in excellent yields. It could provide a new and expedient way for the preparation of symmetrical and unsymmetrical (Z)‐1,2‐diorganolthio1‐1‐alkenes. |
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| Keywords: | nucleophilic addition regioselectivity alkynes hydrothiolation cesium hydroxide (Z)‐1 2‐diorganolthio1‐1‐alkenes |
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