Enzymatic degradation of chitosan films by collagenase |
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| Authors: | E I Kulish V P Volodina S V Kolesov G E Zaikov |
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| Institution: | (1) Bashkortostan State University, ul. Frunze 32, Ufa, 450074, Bashkortostan, Russia;(2) Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia;(3) Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia |
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| Abstract: | Special features of enzymatic degradation of chitosan samples prepared as films from solutions in acetic acid under the action of collagenase as a nonspecific enzyme are considered. Variations in acid concentration in the casting solution had a substantial effect on the chitosan structure in the film formed and, as a consequence, on the degree of degradation of film samples. The addition of poly(vinyl alcohol) upon the formation of a chitosan film led to an increase in the extent of enzymatic degradation of the film. |
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