Multiresidue-matrix solid-phase dispersion method for determining 16 organochlorine pesticides and polychlorinated biphenyls in fish

Summary An effective, multiresidue-matrix, solid-phase dispersion — extraction (MSPD) and GC-MS method for the determination of 16 organochlorine pesticides (OCPs), as well as polychlorinated biphenyls (PCBs) from the level chlorination in fish is described. The method uses an octadecylsilyl-derivatized silica and Florisil-based MSPD co-column for direct, on-line clean-up. Recoveries calculated from five different fortification levels are >85% in all cases for OCPs, except for heptachlor and 4,4-DDT where recoveries of 78% and 81% are ob-tained, and >95% for PCBs. Detection limits determined for the OCPs vary from 19.6–91.1 ng g^–1, and from 71.4–111.2 ng g^–1 for the two to five chlorine-containing PCBs. The method has been applied to the analysis of fish grown in Er-Jen river (Taiwan) and method may serve as a screening protocol for the determination of OCPs and PCBs in fish.