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Efficient synthesis of fluorinated biphenyl derivatives via Pd-catalyzed Suzuki coupling reactions in aqueous solvents at room temperature
Authors:Mengping Guo  Fangfang Jian
Affiliation:a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, PR China
b New Materials and Function Coordination Chemistry Laboratory, Qingdao University of Science and Technology, Qingdao 266042, China
c Department of Chemistry, Yichun Institute, Yichun 336000, China
Abstract:A variety of fluorinated biphenyl derivatives were obtained in good yields in aqueous solvents at room temperature by Suzuki coupling reaction of aryl bromides and aryl boronic acid in the presence of high activity catalyst—some air-stable hemilabile Psingle bondO coordinated cyclopalladated complexes. The structures of above catalysts were characterized by element analyses, IR, 1H NMR, 13C NMR and 31P NMR.
Keywords:Cyclopalladated catalyst   Suzuki coupling reaction   Fluorinated biphenyl derivatives
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