Ytterbium triflate as an efficient catalyst for one-pot synthesis of substituted imidazoles through three-component condensation of benzil, aldehydes and ammonium acetate |
| |
| Authors: | Li-Min Wang Yong-Hong Wang Yin-Fang Yao Bo Liu |
| |
| Affiliation: | a Laboratory for Advanced Materials, Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Lu, Shanghai 200237, People's Republic of China
b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, People's Republic of China |
| |
| Abstract: | Yb(OTf)3 has been found to be an extremely efficient catalyst for the preparation of imidazoles derivatives via three-component coupling reactions of benzil, aldehydes and ammonium acetate under mild conditions. The process presented here is operationally simple, environmentally benign and has excellent yield. Furthermore, the catalyst can be recovered conveniently and reused for at least three reaction cycles without any loss of activity. |
| |
| Keywords: | Ytterbium trifluoromethanesulfonate [Yb(OTf)3] Benzil Aldehyde Imidazole |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
