首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Enzymatic self-wiring
Institution:1. Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, ON M5S 3E5, Canada;2. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, ON M5S 3G9, Canada;3. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada;4. Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada;1. Department of Bioengineering, Stanford University, Stanford, CA, USA;2. Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA;3. Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA;4. Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA;5. Department of Chemistry, RWTH Aachen University, Aachen, Germany;6. Department of Comparative Medicine, Stanford University, Stanford, CA, USA;7. Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA
Abstract:Redox conducting polymers “Wires” have been widely used as a electron mediators between enzyme active sites and electrode surfaces in electrochemical biosensors. We report that a peroxidase is able to generate a molecular wire through its own enzymatic catalyzed reaction. The catalytic reaction is the polymerization of aniline to form conducting polyaniline. The polyaniline molecular wire is then capable of transducing the enzyme’s catalytic turnover into an electrochemical signal. In effect we demonstrate the selective bridging of the gap between nano and macroscales in a functional fashion (electrical conductivity) using the catalytic capabilities of the nanostructure.
Keywords:
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号