| DNA与Rt、VB2相互作用的电化学性质 |
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| 引用本文： | 包晓玉,党元林,曹书杰,陈欣,陈建国. DNA与Rt、VB2相互作用的电化学性质[J]. 化学研究与应用, 2004, 16(4): 522-524 |
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| 作者姓名： | 包晓玉 党元林 曹书杰 陈欣 陈建国 |
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| 作者单位： | 南阳师范学院化学系,河南,南阳,473061;南阳师范学院化学系,河南,南阳,473061;南阳师范学院化学系,河南,南阳,473061;南阳师范学院化学系,河南,南阳,473061;南阳师范学院化学系,河南,南阳,473061 |
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| 基金项目： | 河南省教育厅自然科学研究项目基金资助(20021800002) |
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| 摘 要： | 芦丁(Rt)是存在于多种植物体中的一种多羟基黄酮化合物，是某些中草药的有效成分。本文在前文基础上着重对芦丁、VB2在玻碳电极上的电化学性质、二者与DNA相互作用的机理等方面的差异进行比较，这对维生素类药物与生物大分子相互作用的研究与应用具有重要意义。
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| 关 键 词： | DNA 芦丁 维生素B2 循环伏安法 |
| 文章编号： | 1004-1656(2004)04-0522-03 |
| 修稿时间： | 2003-10-16 |
A Comparison of electrochemical investigation on interactions between DNA with rutin and vitamin B2 |
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| BAO Xiao-yu,CAO Shu-jie,CHEN Xin,CHEN Jian-guo. A Comparison of electrochemical investigation on interactions between DNA with rutin and vitamin B2[J]. Chemical Research and Application, 2004, 16(4): 522-524 |
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| Authors: | BAO Xiao-yu CAO Shu-jie CHEN Xin CHEN Jian-guo |
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| Affiliation: | BAO Xiao-yu~*,CAO Shu-jie,CHEN Xin,CHEN Jian-guo |
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| Abstract: | In the paper we compare rutin with vitamin B_2 in electrochemical investigation,electrochemcial parameters of adding DNA.It shows that both reduction and oxidation peak currents of rutin or vitamin B_2 decrease with no change in the peak potentials,when DNA is added in rutin or vitamin B_2 solution.An electrochemical inactive supramolecular complex DNA-Rt or DNA-VB_2 was formed.The decrease in peak current was proportional to DNA concentration and can be used to determine DNA concentration.Change of peak current with the concentration of rutin or vitamin B_2 is linear in sure range and can be used to determine rutin or vitamin B_2concentration.A satisfactory result was obtained for the determination of rutin or vitamin B_2 in tablet. |
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| Keywords: | DNA rutin vitamin B_2 cyclic voltammetry |
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