Investigations of 2-substituted imidazoles. 2. Synthesis and electrophilic substitution of 1-methyl-2-(thienyl-2)imidazole. A convenient method of methylation of 2-R-imidazoles

We have synthesized 2-(thienyl-2)imidazole and its N-methyl derivative. The latter product was obtained by nitration, bromination, acylation, and formylation, occurring as a rule on the thiophene ring. A general method for methylating 2-R-imidazoles with methyl iodide KOH-dimethoxy ethane is proposed.For Communication 1 see 1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1414–1418, October, 1991.