Novel,efficient and stereospecific synthesis of xylo-(2R,3S,4S)-phytosphingosine and threo-(2R,3R)-sphingosine |
| |
| Affiliation: | 1. College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China;2. Department of Environmental Engineering and Chemistry, Luoyang Institute of Science and Technology, Luoyang 471023, PR China;1. Department of Chemistry, Tsinghua University, Beijing 100084, China;2. Institute of Chemical Materials, CAEP, Mianyang 621900, China;1. Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan;2. Graduate School of Bioscience and Bioindustry, Tokushima University, Tokushima 770-8513, Japan |
| |
| Abstract: | The stereo- and regioselective elaboration of a bromohydrin from an olefinic precursor and Pummerer ene reaction for carboncarbon bond formation are the key steps in a novel and flexible synthesis of xylo-phytosphingosine and threo-sphingosine. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
