NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells |
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| Authors: | Nadia Ferlazzo Salvatore Condello Monica Currò Giulia Parisi Riccardo Ientile Daniela Caccamo |
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| Institution: | (1) Department of Biochemical, Physiological and Nutritional Sciences, University of Messina, Messina, Italy |
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| Abstract: | Background Perinatal exposure to hyperhomocysteinemia might disturb neurogenesis during brain development and growth. Also, high levels
of homocysteine trigger neurodegeneration in several experimental models. However, the putative mechanisms of homocysteine-induced
toxicity in the developing nervous system have poorly been elucidated. This study was aimed to investigate homocysteine effects
in undifferentiated neuroblastoma cells, Neuro2a. |
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