Biphenyls, a new class of compound that inhibits platelet-activating factors |
| |
| Authors: | T Takeya N Takeuchi T Kasama K Mayuzumi H Fukaya S Tobinaga |
| |
| Affiliation: | Showa College of Pharmaceutical Sciences, Tokyo, Japan. |
| |
| Abstract: | Honokiol (1), a constituent of Magnoliae cortex, and related synthetic biphenyls inhibited the platelet aggregation induced by a few aggregating agents. In particular, compounds 3, 5, and 10 had an inhibitory effect on platelet activating factor (PAF), which provides a new class of PAF inhibitor. |
| |
| Keywords: | |
|
|
