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A search for sources of drug resistance by the 4D-QSAR analysis of a set of antimalarial dihydrofolate reductase inhibitors
Authors:Osvaldo Andrade Santos-Filho  Anton J Hopfinger
Institution:(1) Laboratory of Molecular Modeling and Design (M/C-781), University of Illinois at Chicago, College of Pharmacy, 833 South Wood Street, Chicago, IL, 60612-7231, U.S.A
Abstract:
Keywords:dihydrofolate reductase  malaria  mutation  pharmacophore  QSAR
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