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An efficient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction
Authors:Ming-Yu WuMing-Qi Wang  Kun LiXing-Wen Feng  Ting HeNa Wang  Xiao-Qi Yu
Affiliation:Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China
Abstract:An efficient green route for the synthesis of substituted dihydrofurans was developed through a simple base-catalyzed, tandem reaction of nitrostyrene with 1,3-dicarbonyl compounds. The desired products were prepared with a large substrate scope and in excellent yields (up to 95%).
Keywords:Dihydrofuran   Tandem reaction   Nitrostyrene   1,3-Dicarbonyl compounds
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