An efficient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction |
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Authors: | Ming-Yu WuMing-Qi Wang Kun LiXing-Wen Feng Ting HeNa Wang Xiao-Qi Yu |
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Affiliation: | Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China |
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Abstract: | An efficient green route for the synthesis of substituted dihydrofurans was developed through a simple base-catalyzed, tandem reaction of nitrostyrene with 1,3-dicarbonyl compounds. The desired products were prepared with a large substrate scope and in excellent yields (up to 95%). |
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Keywords: | Dihydrofuran Tandem reaction Nitrostyrene 1,3-Dicarbonyl compounds |
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