A convenient Synthesis of 6-Substituted-2,2-Dimethyl-2H-1-Benzopyrans |
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| Authors: | Charles Z. Ding |
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| Affiliation: | The Bristol-Myers Squibb Pharmaceutical Research Institute , P. O. Box 4000, Princeton, 08543-4000, NJ |
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| Abstract: | Various 2,2-dimethyl-6-functional-2H-1-benzopyrans were prepared via a halogen-metal exchange reaction followed by treatment with electrophiles. These 6-functionalized chromenes are important synthetic intermediates for preparation of benzopyran-based potassium channel openers. |
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