An Improved Synthesis of 4-Cycloheptene-1-Carboxylic Acid |
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Authors: | Donald J Marquardt Martin Newcomb |
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Institution: | 1. Department of Chemistry Texas , A&2. M University College Station , Texas, 77843 |
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Abstract: | Modification of the method of Stork and Landesman (J. Am. Chem. Soc. 1956, 78, 5129) permitted the synthesis of the title acid (1) in 58% yield from a cyclopentanone enamine. Acid 1 is a useful intermediate for the preparation of 4-substituted cycloheptenes in good yields. |
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