Enantioselective Catalytic Borane Reductions of Achiral Ketones: Synthesis and Application Of New Catalysts Prepared from (S)-Tert-Leucine and (S)-Azetidinecarboxylic Acid |
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| Authors: | W Behnen Ch Dauelsberg S Wallbaum J Martens |
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| Institution: | Fachbereich Chemie , Universit?t Oldenburg , Ammerl?nder Heerstra? 114—118, D-2900, Oldenburg i. O., Germany |
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| Abstract: | Enantiocontrolled reduction of prochiral ketones with borane in the presence of homochiral amino alcohols 1—3 as enantioselective catalysts afforded the corresponding secondary alcohols in moderate to high (69 to >99 %) optical yields. |
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