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A Convenient Synthesis of Aminoacids by ZnBr2 Promoted Reaction of Ketene bis(Trimethylsilyl) Acetals with Aldimines |
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| Authors: | M. Mladenova M. Bellassoued |
| Affiliation: | 1. Institute of Organic Chemistry, Bulgarian Academy of Sciences , 1113 , Sofia , Bulgaria;2. Laboratoire de Synthèse Organomètallique (URA 408), Université P. et M. Curie , 4, Place Jussieu, Bǎt, F, 75230, Paris Cedex , 05 , France |
| Abstract: | The ZnBr2 promoted addition of ketene bis(trimethylsilyl) acetals to aromatic aldimines affords β-arylaminoacids in good to excellent yields. Under the same reaction conditions vinylic ketene bis(trimethylsilyl) acetals give exclusively or mainly δ - phenylaminoacids. |
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