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The Total Synthesis of the Anti-Coccidial Agents Ws-5995 |
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| Authors: | Thomas C McKenzie Woo-Baeg Choi |
| Institution: | Chemistry Department , University of Alabama , Tuscaloosa, AL, 35487 |
| Abstract: | A total synthesis of the three anti-coccidial agents WS-5995 A, B, and C by a Diels-Alder route is described. An intramolecular lactonization involving the displacement of a chlorine atom on a naphthoquinone was the key step in the synthesis of A. |
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