A Convenient Synthesis of Cephem-1R-sulfoxides |
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Authors: | R G Micetich R Singh M P Singh C C Shaw |
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Institution: | 1. Faculty of Pharmacy and Pharmaceutical Sciences , University of Alberta , Edmonton, Alberta, Canada , T6G 2N8;2. Ayerst Laboratories , Montreal, Quebec, Canada |
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Abstract: | 7-Amidocephalosporins are converted to the 7-diacylaminocephalosporins, which are oxidised exclusively to the 7-diacylamino-1α-sulfoxides. These compounds with benzylamine produce the 7-amidocephem-1α-sulfoxides. |
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