Regioselective Synthesis of Flindersine Analogues |
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| Authors: | K C Majumdar P K Choudhury |
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| Institution: | Department of Chemistry , University of Kalyani , Kalyani 741 235, West Bengal, India |
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| Abstract: | 6-Alkylpyrano 3,2-c] quinolin-5(2H)-ones(11a-e) were obtained in excellent yields by simply refluxing propynyl and butymyl ethers (6) of 4-hydroxy-1-alkylquinolin-2H-ones (2) in chlorobenzene for 10h, 5-Prop-2-ynyloxy-2H-pyrano 3,2-c] quinoline (12) was also obtained from the thermal rearrangement of 2,4-bis prop-2-ynyloxyquinoline (4). |
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