A Study on the Stability of 5,5-Diamino-substituted-1,4,2-oxathiazoline Derivatives |
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| Authors: | Keum Shin Jung Hong Jung Lee Hyun Nam Song Jae Nyoung Kim |
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| Institution: | Department of Chemistry , Chonnam National University , Kwangju , 500-757 , Korea |
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| Abstract: | 5,5-Diamino-substituted-1,4,2-oxathiazoline derivatives 3 as potential prodrugs, which were easily prepared from hydroximoyl chlorides 1 and the appropriate thiourea derivatives 2, were decomposed instantaneously into isothiocyanates 4 and the corresponding urea derivatives 5 irrespective of the substituents. |
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