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An Enantioselective Chemoenzymatic Synthesis of the Four 1-Amino 2-Methylcyclopropane Carboxylic Acids |
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| Authors: | F. Rusconi di Lugano J. Monteiro C. Fliche J. Braun F. Le Goffic |
| Affiliation: | Laboratoire de Bioorganique et de Biotechnologies , UA 1389, C.N.R.S. , 11 rue Pierre et Marie Curie, 75231, PARIS CEDEX 05, France |
| Abstract: | Racemic 2-methylcyclopropane dicarboxylic acid dimethyl ester undergoes selective enzymatic reactions to give enantiomerically pure monocarboxylic acids which by classical organic chemistry lead to the four 1-amino 2-methyl cycloproane carboxylic acids. |
| Keywords: | Aldehyde amines ketone oxidation sodium nitrite |