A Novel and Efficient Synthesis of 5-(Hydroxymethyl) Thiazole: An Important Synthon for Preparing Biologically Active Compounds |
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Authors: | Francis A. J. Kerdesky Louis S. Seif |
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Affiliation: | Process Research, Department 45LPharmaceutical Products Division , Abbott Laboratories , Abbott Park, Illinois, 60064 |
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Abstract: | A novel and efficient synthesis of 5-(hydroxymethyl) thiazole, an important synthon for the preparation of biologically active compounds, is described. The research also provides additional insight into the properties of halothiazoles. |
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