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Vanillin (1) As Starting Material for the Synthesis of Isomeric Phthalides |
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| Authors: | Paulo R R Costa ClÁUdio C Lopes Ros[acaron]ngela S C Lopes Maria F G Marinho Rosane N Castro |
| Institution: | 1. Núcleo de Pesquisas de Produtos Naturais , Univcrsidade Federal do Rio de Janeiro, Centro de Ciěncias da Saúde , Bloco H, 21941, Rio de Ja neiro, RJ, Brazil;2. Departamento de Química Analítica , Instituto de Química , UFRJ;3. Departamento de Tecnologia Farmacěutica , Facuj. dade de Farmácia , UFRJ |
| Abstract: | Phthalides have bcen employed as useful intcriucdiates in tic sqrnthcsis of my condcnscld aromatic carbocyclic and heterocyclic compounds, including several natural products In this paper we report two alternative synthetic pathways for the preparation of phthalides as shown for the synthesis of the isomeric pairs of compounds 5a-d and 7a-d. |
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