Ring Opening of a Fatty Epoxide by Diethylacetamido Malonate in Basic Medium by Phase Transfer Catalysis or Under Microwave Irradiation |
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| Authors: | D Abenhaïm A Loupy C Mahieu D Séméria |
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| Institution: | 1. Laboratoire des Réactions Sélectives sur Supports , CNRS UA 478 ICMO, Université de Paris-Sud , B[acaron]timent 410, 91405, Orsay Cedex, France;2. L'Oréal S.A., I , Avenue E. Schueller, 93601, Aulnay sous Bois, France |
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| Abstract: | A fatty epoxide (tetradecyl-oxirane) is reacted with diethyl acetamidomalonate in basic medium, with or without solvent under solid-liquid phase transfer catalysis with LiCl, or under microwave irradiation on supported reagents (KF/Al2O3/LiCl). The main product is a lactone which is formed after epoxide ring opening and subsequent cyclisation. We put here into evidence, for the first time, the conjugated advantages of “dry media” reactions, lithium salt effects and microwave irradiation. |
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| Keywords: | D‐(?)‐Quinic acid" target="_blank">D‐(?)‐Quinic acid epoxidation quercitol |
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