Convenient Method for Preparation of Dialkylphosphoramidopropionic Acids and Esters |
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| Authors: | Katia Kerdel Michel Baboulène Armand Lattes |
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| Institution: | Laboratolre des Interactions Moléculaires et Réactivité Chimique et Photochimique, UA (CNRS) 470 , Universoté Paul Sabatier , 118 route de Narbonne, 31062, Toulouse Cédex, FRANCE |
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| Abstract: | Silylation at the alpha position of N-propargyl dialkylphosphoramidates enables preparation of dialkylphosphoramido propionic acids in 50–60% yield after hydroboration/oxidation. Treatment with Amberlyst 15 resin in the presence of methanol leads to a quantitative yield of the corresponding esters. |
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