Application of the Curtius Rearrangement in a Convenient Preparation of 3-Aminopyrazinecarboxylic Acid,Methyl Ester |
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| Authors: | Jiong J. Chen Jack M. Hinkley Dean S. Wise Leroy B. Townsend |
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| Affiliation: | 1. Department of Chemistry, College of Literature, Science, &2. The Arts;3. Department of Medicinal Chemistry, College of Pharmacy , The University of Michigan , Ann Arbor, MI, 48109 |
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| Abstract: | An efficient and convenient synthesis of 3-aminopyrazinecarboxylic acid, methyl ester (7) has been achieved through the use of a Curtius rearrangement. |
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