Enolate Alkylations with Vinylphosphonates |
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| Authors: | S. D. Darling Florentina N. Muralidharan V. E. Muralidharan |
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| Affiliation: | Department of Chemistry , The University of Akron , Akron, Ohio, 44325 |
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| Abstract: | A remarkable feature of diethyl-1,3-butadiene-phosphonate, unlike the dienephosphonium salts,2,3 is that it undergoes a simple Michael addition with enolates of aldehydes and ketones without the loss of the phosphorus group.4 Whether such a difference in reactivity exists between the two-carbon reagents, vinyltriphenylphosphonium bromide 1 5 and diethyl vinylphosphonate 2 6 is the subject of this investigation. |
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