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Palladium Acetate Mediated Synthesis of 3,4-Benzo and Naphtho-β-Carbolines |
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| Authors: | A Jeevanandam P C Srinivasan |
| Institution: | Department of Organic Chemistry , University of Madras , Guindy Campus, Madras, 600 025, INDIA |
| Abstract: | An efficient synthesis of 2-(N-arylaminomethyl)indole derivatives 5 in good yields in four steps from 2-bromomethyl-3-phenylthio-1-benzenesulfonyl indole1 is reported. Palladium acetate mediated cyclisation of 5 gives benzo and naphtho-ß-carbolines (6 & 7). |
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