A Mild and Convenient Oxidation of Aryl Nitriles to Aryl Amides by Aqueous Sodium Perborate |
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| Authors: | Kathryn L. Reed John T. Gupton Traci L. Solarz |
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| Affiliation: | Department of Chemistry , University of Central Florida , Orlando, FL, 32816 |
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| Abstract: | A series of benzonitriles has been reacted with sodium perborate in water and a cosolvent to produce the corresponding amides in good yield. The procedure is a mild and convenient alternative for the synthesis of aryl amides. |
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| Keywords: | Asymmetric synthesis biocatalysis deuterium NMR spectroscopy |
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