|
|||||
|
|
A Novel Route to N-Styrylamides |
|
| Authors: | A. R. Katritzky A. V. Ignatchenko H. Lang |
| Affiliation: | Center for Heterocyclic Compounds, Department of Chemistry , University of Florida, Gainesville , FL, 32611-7200, USA |
| Abstract: | A general synthesis of N-styrylamides starting from amides and phenylacetaldehyde is described. Condensation of the amide, aldehyde and benzotriazole affords N-(1-benzotriazol-l-yl-2-phenylethyl)amides 2 from which the benzotriazole molecule is smoothly eliminated. |
| Keywords: | |