An Alternative Generation of a 13.14-Carbon-Carbon Triple Bond in Prostanoids |
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| Authors: | U. Klar P. Deicke A. Pletsch |
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| Affiliation: | Research Laboratories of Schering AG, Müllerstr , 170-178, W-1000, Berlin, 65, FRG |
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| Abstract: | A novel HBr elimination method for the introduction of a 13.14-triple bond into the prostanoid framework starting from readily available vinyl bromides is described. The transformation can be performed even on sensitive compounds in the presence of various functional groups in synthetically useful yields. |
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