Fluorotamoxifen. A Caveat on the Generality of Electrophilic Destannylation |
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Authors: | David E Seitz Larry C Blaszczak |
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Institution: | 1. Indiana University School of Medicine, Department of Medicine , 926 West Michigan Street, Indianapolis, IN, 46223;2. The Lilly Research Laboratories , Eli Lilly and Company Lilly Corporate Center , Indianapolis, IN, 46285 |
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Abstract: | A one-step synthesis of fluorotamoxifen from tamnoxifen is described. Attempts to achieve synthesis of the title compound by fluorodestannylation or transmetallation were unsuccessful. |
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